Spironolactone and calcification
نویسندگان
چکیده
منابع مشابه
Spironolactone ameliorates arterial medial calcification in uremic rats: the role of mineralocorticoid receptor signaling in vascular calcification.
Vascular calcification (VC) is a critical complication in patients with chronic kidney disease (CKD). The effects of spironolactone (SPL), a mineralocorticoid receptor (MR) antagonist, on VC have not been fully investigated in CKD. The present in vivo study determined the protective effects of SPL on VC in CKD rats. Rats were divided into a control group and four groups of rats with adenine-ind...
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• Objective: To assess the impact of interventions to increase the use of spironolactone in patients with congestive heart failure (CHF) due to ventricular systolic dysfunction. • Methods: Charts of patients admitted to the medicine department of a single hospital with a primary diagnosis of class IV CHF and left ventricular ejection fraction of 40% or less were randomly selected and reviewed. ...
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Gynecomastia is benign enlargement of male breast, drug-induced gynecomastia accounts for about 25%. We are reporting a case of spironolactone-induced unilateral gynecomastia. A 52-year-old male patient receiving multiple antihypertensives including hydrochlorothiazide presented with muscle weakness and easy fatigability. Investigations revealed hypokalemia; he was advised to stop hydrochloroth...
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Dr. Michael M. Hirschl, Department of Emergency Medicine, New General Hospital, Währinger Gürtel 18-20, A-1090 Vienna (Austria) Admission Dear Sir, Hyponatremia is the most common electrolyte abnormality observed in a general hospitalized population, seen in about 2% of patients [1]. Common causes of hyponatremia are the syndrome of inappropriate secretion of antidiuretic hormone, water intoxic...
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ژورنال
عنوان ژورنال: Nature Reviews Nephrology
سال: 2013
ISSN: 1759-5061,1759-507X
DOI: 10.1038/nrneph.2013.6